View Full Version : Statin Found to Protect Heart in People With Inflammation and Normal Cholesterol

Donald Lee
11-12-2008, 12:26 AM
I'm sure a lot of you guys have already heard about the Jupiter study, but I thought it'd be worth posting anyways.

Statin Crestor Found to Protect Heart in People With Inflammation and Normal Cholesterol (http://health.usnews.com/articles/health/2008/11/10/health-buzz-cholesterol-drug-crestors-coup-and-other-health-news.html):

Half of all heart attack victims have perfectly normal cholesterol levels, and many have no risk factors at all. Experts have recently come to believe that one hidden culprit is chronic inflammation, which turns arteries into plaque magnets. But they haven't known whether treating inflammation could actually protect the heart. A new landmark finding suggesting that is the case could affect millions of seemingly healthy people, Deborah Kotz reports.

If confirmed in further studies, the research, published in the current New England Journal of Medicine, could transform screening for heart disease. Nearly 18,000 people with normal cholesterol levels and no heart disease but high levels of inflammation (as measured by a marker called C-reactive protein) were randomly assigned to take either the cholesterol-lowering statin known as Crestor, which has anti-inflammatory effects, or a placebo. Over two to five years of treatment, the people taking a statin had about a 50 percent lower risk of heart attack or stroke and a 20 percent lower risk of dying of any cause compared with those who took placebos. They also had a 46 percent lower rate of bypass surgeries and angioplasties.

Crestor isn't the only drug that may fight inflammation. In October, Sarah Baldauf listed 12 things you should know about aspirin, which is one of the cheapest anti-inflammatory drugs available.


That article talks more about the research.

Mike ODonnell
11-12-2008, 07:39 AM
I think this was already covered in another post. I can only take so much bad news from the media.