When I think Health and Longevity I think in terms of quality of life experience rather then genetic bias.
For most a small amount of exercise is enough to keep them "healthy" but more importantly the exercise should be linked with something of enjoyment and some sort of fulfilment, possibly stimulating to themselves and involves contact with a close social based support group.
I would think that any Health based program should have at its focus Nutritional concerns at the core
Mental relaxation, visualisation and focus protocols
Joint mobility and body awareness
Socially interactive exercise as above.
The mental and physical awareness and feeling of social connection, I believe play a very a major role in health and physical well being.