Good points you've made. I agree that things like increased BDNF and altered gene expression are incredibly important and beneficial upsides of IF. Currently no research that I am aware of has compared the effects of different amounts of days fasted/week. In every study all subjects fasted on an on/off schedule, with no breaks between cycles. Therefore, it's necessary for us to use the black box to determine what is useful for our purposes. Part of the reason why I failed with a daily fast is because my stress level was already through the roof. I was going to college, working, working out, cooking all of my own food, and buying all of my own food, which placed a higher level of stress on my body as a whole. My day consisted off moving non-stopped all day, worry non-stopped all day, for all waking hours, even when eating. I think that all of this combined with IF is what threw me over the edge. It was just too much stress from all sources. Now that I have some time to relax and just work and concentrate on objectives that I'm interested in pursuing (taking a semester off from college) I will likely add IF back in on a regular basis so that I can actually sit down and relax and enjoy my meals worry-free. With this in mind, it's easy to see that the implementation of IF in domesticated humans will vary greatly from on individual to another based on their lifestyle, schedule, and overall stress level. When you're already stressed to the max, adding in some little stressors in an attempt to produce a hormetic effect is going to do more harm than good. Some people may be able to fast every single day fro 20 hours. Other maybe not at all due to excessive stress.
There are dreams we’re taught are normal, whether it’s money or success or any of those things, but we shouldn’t believe in those things if they are not important to us. There is an ocean between our real lives and what is expected of us.” -Tim Lambesis