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Old 06-08-2007, 10:42 AM   #5
Brad Hirakawa
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Join Date: Oct 2006
Location: San Diego
Posts: 169
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Several theories out there; metabolites and transporters, variations in p450 activity and pharmacokinetics, drug-drug interaction, ubiquitin proteasome pathway problems, etc. etc. Just off the top of my head, Iím sure there is more information out there, probably on wikipedia by now.

I think youíre right Robb, statins appear to have anti-inflammatory effects in several systems. Very interesting research going on in that realm, but Iím sworn to secrecy.

Cytochrome p450ís, skeletal muscle machinery/biochemistry...Ö mixing steroids and statins..... that is just really stupid.

Brad
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