I can only say that fat burners (without ephedrine) turned me manic and made my husband rightly threaten to institutionalize me.
I slept only 3 hours a night with them. I couldn't eat because they made me nervous. I sweat as profusely as a sumo running stairs, and my pulse on first waking was like 106 or something.
That's only what I noticed from four days of taking Hot Rox.