What are you doing for exercise/conditioning right now?
IMO, I would start off your regime including starting strength, not doing isometrics (i believe you mean isolation exercises?). I don't have experience from a coaching perspective, but I started with starting strength/paleo when I was heavier, and I got lean and strong really quick. I cheated a little and did some cardio on off days, but still worked for me. Someone with more experience coaching will definitely have something to add, but that was really the only glaring thing that I saw. Power, flexibility, mental barriers will all come with good training, the last is part training but mostly food quality.