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Old 06-25-2011, 05:22 AM   #1
Darryl Shaw
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Join Date: Apr 2008
Posts: 708
Default The Effects of Intermittent or Continuous Energy Restriction on Weight Loss.

Quote:
The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomised trial in young overweight women.

Abstract


Background

The problems of adherence to energy restriction in humans are well known.

Objective

To compare the feasibility and effectiveness of IER with CER for weight loss, insulin sensitivity and other metabolic disease risk markers.

Design

Randomised comparison of a 25% energy restriction as IER (~2266 kJ/day for 2 days/week) or CER (~6276 kJ/day for 7 days/week) in 107 overweight or obese (mean [±SD] body mass index 30.6 [±5.1] kg/m2) premenopausal women over 6 months. Weight, anthropometry, biomarkers for breast cancer, diabetes, cardiovascular disease and dementia risk; insulin resistance (HOMA), oxidative stress markers, leptin, adiponectin, IGF-1 and IGF binding proteins 1 and 2, androgens, prolactin, inflammatory markers (high sensitivity C-reactive protein and sialic acid), lipids, blood pressure and brain derived neurotrophic factor were assessed at baseline and after 1, 3 and 6 months.

Results

Last observation carried forward analysis showed IER and CER are equally effective for weight loss, mean (95% confidence interval [CI]) weight change for IER was −6.4 (−7.9 to −4.8) kg vs.−5.6 (−6.9 to −4.4) kg for CER (P value for difference between groups = 0.4). Both groups experienced comparable reductions in leptin, free androgen index, high sensitivity C-reactive protein, total and LDL cholesterol, triglycerides, blood pressure and increases in sex hormone binding globulin, IGF binding proteins 1 and 2. Reductions in fasting insulin and insulin resistance were modest in both groups, but greater with IER than CER; difference between groups for fasting insulin −1.2 [−1.4 to −1.0] μU/ml, and insulin resistance −1.2 [−1.5 to −1.0] μU/mmol/L (both P=0.04).

Conclusion

IER is as effective as CER in regards to weight loss, insulin sensitivity and other health biomarkers and may be offered as an alternative equivalent to CER for weight loss and reducing disease risk.
http://www.ncbi.nlm.nih.gov/pmc/arti...4/?tool=pubmed
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Old 06-27-2011, 02:47 AM   #2
Wayne Riddle
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Default

Quote:
young overweight women.
So if you take overweight people and have them lose weight their health markers improved. Who would have thought...
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Old 06-28-2011, 12:28 AM   #3
Willem Koster
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Join Date: Aug 2007
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Originally Posted by Wayne Riddle View Post
So if you take overweight people and have them lose weight their health markers improved. Who would have thought...
Also, if you eat less you lose weight ... another shocker.
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Old 06-28-2011, 02:35 AM   #4
Wayne Riddle
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Join Date: Nov 2009
Posts: 115
Default

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Originally Posted by Willem Koster View Post
Also, if you eat less you lose weight ... another shocker.
Wow, that study was a two-fer!

I'm in the wrong line of work...
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